Staff profile

Journal Article

• PglZ from Type I BREX phage defence systems is a metal-dependent nuclease that forms a sub-complex with BrxB
  Readshaw, J. J., Doyle, L. A., Puiu, M., Kelly, A., Nelson, A., Kaiser, A. J., McGuire, S. F., Peralta Acosta, J., Smith, D. L., Stoddard, B. L., Kaiser, B. K., & Blower, T. R. (2025). PglZ from Type I BREX phage defence systems is a metal-dependent nuclease that forms a sub-complex with BrxB. Nucleic Acids Research, 53(12), Article gkaf540. https://doi.org/10.1093/nar/gkaf540
• Diverse Durham collection phages demonstrate complex BREX defence responses
  Kelly, A., Went, S. C., Mariano, G., Shaw, L. P., Picton, D. M., Duffner, S. J., Coates, I., Herdman-Grant, R., Gordeeva, J., Drobiazko, A., Isaev, A., Lee, Y.-J., Luyten, Y., Morgan, R. D., Weigele, P., Severinov, K., Wenner, N., Hinton, J. C., & Blower, T. R. (2023). Diverse Durham collection phages demonstrate complex BREX defence responses. Applied and Environmental Microbiology, 89(9), Article e00623-23. https://doi.org/10.1128/aem.00623-23
• Toxin–antitoxin systems as mediators of phage defence and the implications for abortive infection
  Kelly, A., Arrowsmith, T., Went, S., & Blower, T. (2023). Toxin–antitoxin systems as mediators of phage defence and the implications for abortive infection. Current Opinion in Microbiology, 73, Article 102293. https://doi.org/10.1016/j.mib.2023.102293
• The engulfasome in C. difficile: Variations on protein machineries
  Kelly, A., & Salgado, P. S. (2019). The engulfasome in C. difficile: Variations on protein machineries. Anaerobe, 60, 102091. https://doi.org/10.1016/j.anaerobe.2019.102091